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MMP-7 gene silencing suppresses invasiveness of BxPc-3 cells. BxPc-3 cells were transfected with scrambled siRNA (siRNA-A) or MMP-7 siRNA as described in Materials and methods. (A) Western blot analysis of MMP-7 was evaluated as described in Fig. 5. (B) Invasion of BxPc-3 cells through Matrigel was determined as described in Fig. 4. Each bar represents the mean ± SD of three experiments. Statistical analysis by ANOVA. *P<0.05.
