Table II.
Gene | Description | Fold change |
---|---|---|
BIRC5 | Baculoviral IAP repeat-containing 5 (survivin) | 0.85±0.12 |
CCNB1 | Cyclin B1 | 0.87±0.03 |
HSP90AA1 | Heat shock protein 90 kDa α (cytosolic), class A member 1 | 0.89±0.02 |
IL-6 | Interleukin-6 | 0.86±0.04 |
KRAS | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.86±0.04a |
MMP-7 | Matrix metalloproteinase-7 | 0.67±0.14a |
MMP-9 | Matrix metalloproteinase-9 | 0.79±0.08 |
RELB | Transcription factor RelB | 0.79±0.10 |
TGFB3 | Transforming growth factor β-3 | 0.82±0.02 |
DNA-microarray analysis was performed as described in Materials and methods. BxPc-3 cells were treated with PTE (0 and 5.0 μg/ml) for 24 h. Data are the means ± SD (n=3). Fold change PTE vs. control. Statistical significance.
P<0.05.