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. 2013 Jul 2;8(7):e65505. doi: 10.1371/journal.pone.0065505

Figure 2. Effect of chronic ICV ghrelin infusion on the tibia trabecular bone phenotype.

Figure 2

(A) Trabecular bone volume expressed as percentage of total tissue volume (BV/TV). (B) Trabecular thickness (Tb.Th). (C) Trabecular number (Tb.N). (D) Trabecular separation (Tb.Sp). (E) Trabecular pattern factor (Tb.Pf). (F) Structure model index (SMI); a lower SMI indicate plate-like structure, whereas a higher SMI indicate sphere-like structure. (G) Trabecular volumetric BMD. (H) Representative microCT images of the proximal tibia. Three groups of rats (4–6 per group) were infused for 21 days with saline or ghrelin (1.5 μg/day). Rats infused with ghrelin were ad lib-fed or pair-fed (to saline-infused rats). * P<0.05; † P<0.1. Data are presented as the mean ± SEM.