Table 2. Accuracy of the automatic atlas-based segmentation.

Region	Automatic-Manual 1	Automatic-Manual 2	Interobserver
Frontal cortex	0.8946	0.9003	0.8993
Medial frontal cortex	0.9049	0.8754	0.8442
Cingulate cortex	0.9494	0.8891	0.8737
Piriform cortex	0.7576	0.7874	0.7984
Entorhinal cortex	0.8945	0.8098	0.8681
Parietal cortex	0.8813	0.8847	0.8926
Occipital cortex	0.9437	0.8175	0.8386
Insular cortex	0.7319	0.7366	0.7528
Temporal cortex	0.9849	0.8737	0.8797
External capsule	0.9221	0.7148	0.7051
Internal capsule	0.9522	0.8365	0.8936
Corpus callosum	0.9780	0.8647	0.8895
Anterior commissure	0.8469	0.7109	0.7856
Periventricular white matter	0.9788	0.7666	0.7735
Subcortical white matter	0.7476	0.8359	0.8231
Corona radiata	0.8873	0.7447	0.7547
Fimbria of hippocampus	0.7903	0.7452	0.7191
Fornix	0.8093	0.7286	0.7547
Claustrum	0.9564	0.8845	0.8366
Caudate nucleus	0.9842	0.9399	0.9513
Thalamus	0.9729	0.9012	0.8900
Hippocampus	0.9447	0.7755	0.8575
Amygdala	0.8851	0.8364	0.8577
Hypothalamus	0.7051	0.7695	0.7516
Lenticular nucleus	0.9535	0.7679	0.8513
Olfactory bulb	0.6951	0.7652	0.8916
Cerebellar hemispheres	0.9458	0.7679	0.8513
Vermis	0.9580	0.9112	0.9166
Basal forebrain	0.8664	0.7403	0.7305
Forebrain	0.7573	0.7715	0.7481
Diencephalon	0.7741	0.8231	0.8970
Mesencephalon	0.9636	0.9251	0.9336
Pons	0.9316	0.9255	0.9207
Medulla oblongata	0.9995	0.9368	0.9532
Septum	0.9777	0.9296	0.9074

Dice coefficient between the manually delineated brain regions and the brain regions identified by the automatic atlas-based segmentation, and between the manual delineations performed by two different observers.