Figure 3. Effect of treatment on histological parameters between treatment groups at 20 weeks.

H&E staining was performed on gastrocnemius muscle cross sections. Muscle histology (number of degenerating, regenerating and inflammatory foci per field) was averaged over five representative fields of non-overlapping fiber cross-sections (A–C). (A) Average number of degenerating fibers per field. (B) Average number of regenerating fibers per field. (C) Average number of inflammatory cell foci per field per group. (D–G) Representative gastrocnemius muscle cross sectional fields taken from vehicle control (D), LANZO-treated (E), prednisolone-treated (F), and combined treatment (G) groups.