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. 2013 Jul 2;8(7):e67577. doi: 10.1371/journal.pone.0067577

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© 2013 Xiao et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The TNM staging was classified according to the 7th edition of AJCC Cancer Staging Handbook [21], and the location and differentiation of cancerous tissues were determined by surgical and histopathological examination, respectively. There was no significant difference of the CASP8 mRNA expression in cancerous and paracancerous normal tissues from all 99 patients (a). The CASP8 mRNA expression in cancerous tissues from patients with different clinical characteristics showed no significant difference (b–f). A-colon, T-colon, D-colon and Rectum stand for ascending colon, transverse colon, descending colon and rectum, respectively.