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Change in [11C]PBR28 binding (VT) after LPS administration in the one baboon that had a PET scan at baseline and 1h and 4h post-LPS (the other baboons had either a 1h or a 4h scan). (A) MRI from this baboon. (B) [11C]PBR28 binding at baseline. (C) [11C]PBR28 binding 1h post-LPS. (D) [11C]PBR28 binding 4h post-LPS. Abbreviations: LPS, lipopolysaccharide; MRI, magnetic resonance imaging; VT, total volume of distribution.
