Table 1.
Baseline characteristics of REGARDS study participants with an eGFR<60 ml/min per 1.73 m2 by number of ideal Life’s Simple 7 factors
| Characteristic | Overall Population (n=3093) | Number of Ideal Life’s Simple 7 Factors | ||||
|---|---|---|---|---|---|---|
| 0–1 (n=845) | 2 (n=1062) | 3 (n=767) | 4 (n=337) | 5–7 (n=82) | ||
| Age, yr | 72.2 (8.7) | 69.8 (8.2) | 72.2 (8.6) | 73.6 (8.8) | 74.7 (8.6) | 75.3 (9.3) |
| African American, % | 42.3 | 54.4 | 41.1 | 37.9 | 30.0 | 23.2 |
| Men, % | 45.1 | 38.5 | 44.8 | 48.2 | 53.7 | 51.2 |
| Geographic region, % | ||||||
| Stroke belt | 32.6 | 34.1 | 33.4 | 30.1 | 34.1 | 23.2 |
| Stroke buckle | 20.8 | 23.0 | 18.6 | 22.4 | 19.6 | 17.1 |
| Other | 46.6 | 43.0 | 47.9 | 47.5 | 46.3 | 59.8 |
| Household income<$20,000/yr, % | 24.3 | 36.3 | 26.9 | 23.7 | 24.7 | 14.3 |
| Less than high school education, % | 19.2 | 23.1 | 18.6 | 16.8 | 18.1 | 14.6 |
| Physically active, % | 54.0 | 36.8 | 51.0 | 64.2 | 74.5 | 90.2 |
| Current smoker, % | 10.5 | 21.4 | 8.9 | 5.1 | 3.6 | 0.0 |
| Diet factors | ||||||
| Fish consumption, g/wk | 22.0 (29.0) | 24.0 (34.6) | 21.8 (25.7) | 21.0 (28.0) | 19.5 (22.8) | 26.8 (37.7) |
| Sodium intake, mg/d | 2140 (1015) | 2121 (1074) | 2202 (1053) | 2060 (939) | 2175 (981) | 2170 (758) |
| Sugar, mg/d | 249 (203.4) | 226 (197) | 257 (207) | 249 (199) | 273 (219) | 261 (177) |
| Fruits and vegetables, cups/wk | 4.1 (2.3) | 3.9 (2.3) | 4.1 (2.3) | 4.0 (2.3) | 4.2 (2.3) | 5.2 (2.4) |
| Fiber/carbohydrate intake ratio | 0.08 (0.03) | 0.08 (0.03) | 0.08 (0.03) | 0.08 (0.03) | 0.08 (0.03) | 0.09 (0.03) |
| Body mass index, kg/m2 | 29.6 (6.4) | 32.5 (6.0) | 30.4 (6.1) | 27.8 (5.9) | 25.0 (4.5) | 23.6 (4.3) |
| Fasting serum glucose, mg/dl | 105 (37) | 123 (50) | 103 (33) | 96 (22) | 91 (13) | 87 (8) |
| Antiglycemic medication use, % | 31.2 | 65.9 | 31.7 | 14.6 | 3.7 | 1.3 |
| Diabetes mellitus, % | 35.1 | 70.1 | 33.7 | 15.7 | 4.3 | 1.3 |
| Total cholesterol, mg/dl | 186 (43) | 190 (48) | 189 (43) | 184 (42) | 180 (33) | 169 (31) |
| Lipid-lowering medication use, % | 46.3 | 72.4 | 49.0 | 33.8 | 16.2 | 6.1 |
| Systolic BP, mmHg | 130.8 (18) | 133 (18) | 132 (18) | 130 (18) | 128 (17) | 115 (14) |
| Diastolic BP, mmHg | 75 (11) | 75 (11) | 75 (10) | 75 (11) | 73 (10) | 69 (10) |
| Antihypertensive medication use, % | 76.1 | 90.8 | 82.7 | 71.0 | 58.7 | 32.1 |
| Hypertension, % | 80.8 | 90.4 | 85.2 | 76.3 | 65.0 | 31.7 |
| Renin angiotensin system blockers, % | 58.0 | 69.7 | 61.5 | 49.2 | 43.3 | 35.4 |
| Coronary heart disease, % | 31.7 | 38.3 | 32.0 | 27.8 | 25.2 | 23.2 |
| Stroke, % | 13.0 | 14.7 | 13.1 | 12.5 | 10.1 | 9.8 |
| eGFR, ml/min per 1.73 m2 | 47.1 (10.9) | 45.1 (12.0) | 46.9 (10.5) | 48.4 (10.4) | 48.5 (9.8) | 50.6 (8.2) |
| Geometric mean (95% CI) ACR, mg/g | 23.8 (22.3 to 25.4) | 39.4 (34.2 to 45.4) | 23.5 (21.0 to 26.3) | 18.5 (16.4 to 20.8) | 14.4 (12.4 to 16.8) | 13.7 (10.3 to 18.2) |
Supplemental Appendix has listing and definitions of ideal levels for each Life’s Simple 7 factor. ACR, albumin-to-creatinine ratio.