Skip to main content
. 2013 Mar 21;2(3):316–324. doi: 10.1002/cam4.65

Table 1.

Dose escalation scheme and cycle 1 dose limiting toxicity events (DLTs)

Cohort level ABT-510 (mg, twice daily) Bevacizumab (mg/kg, every 14 days) No. of patients No. of DLTs DLT events
1 50 5 3 0
2 50 10 3 0
3 100 10 6 1 Grade 2 GI bleed
Expanded cohort 100 10 22 0

GI, gastrointestinal.