Table 2.
Soluble angiogenic factors | Matrix-derived angiogenic factors | Markers of coagulation | Markers of vascular activation and inflammation | ||
---|---|---|---|---|---|
ANG-2 | PEDF | MMP2 | CRP | E-cadherin | NT-proBNP |
bFGF | PlGF | MMP9 | D-dimer | E-selectin | MCP-1 |
HGF | VEGF-A | Osteopontin | PAI-1 active | Gro-α | P-selectin |
IGFBP1 | VEGF-C | TGFβ1 | PAI-1 total | ICAM-1 | SDF-1 |
IGFBP3 | VEGF-D | TGFβ2 | Tissue factor | IFNγ | TNFα |
PDGF-AA | sVEGFR1 | TSP1 | vWF | IL-6 | VCAM-1 |
PDGF-BB | sVEGFR2 | TSP2 | IL-8 |
ANG-2, angiopoietin-2; bFGF, basic fibroblast growth factor; HGF, hepatocyte growth factor; IGFBP, insulin-like growth factor-binding protein; PDGF, platelet-derived growth factor; PEDF, pigment epithelium-derived factor; PlGF, placental growth factor; VEGF, vascular endothelial growth factor; sVEGFR, soluble vascular endothelial growth factor receptor; MMP, matrix metallopeptidase; TGFβ, transforming growth factor beta; TSP, thrombospondin; CRP, c-reactive protein; PAI-1, plasminogen activator inhibitor-1; vWF, von willebrand factor; Gro-α, growth regulated oncogene-alpha; ICAM-1, intercellular adhesion molecule 1; IFNγ, interferon gamma; IL, interleukin; NT-pron-BNP, N-terminal prohormone brain natriuretic peptide; MCP-1, macrophage chemoattractant protein-1; SDF-1, stromal cell-derived factor-1; TNFα, tumor necrosis factor-α; VCAM-1, vascular cell adhesion molecule 1.