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. Author manuscript; available in PMC: 2014 Jul 24.
Published in final edited form as: J Mol Biol. 2013 Apr 16;425(14):2561–2577. doi: 10.1016/j.jmb.2013.04.012

Figure 1. Structure of the PXR-RXR LBD Complex.

Figure 1

A. 2.8 Å resolution structure of the complex formed between the ligand binding domains (LBDs) of human PXR (cyan, green) and RXRα (magenta, yellow), with the SRC-1 peptides bound to each LBD indicated. B. In the ligand bound complex of PXR and RXRα, the cholesterol-lowering compound SR12813 is contacted by the amino acid side chains indicated.