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. 2013 May 15;19(15-16):1723–1732. doi: 10.1089/ten.tea.2013.0064

FIG. 7.

FIG. 7.

Electron micrograph of hESC-derived mesenchymal cells in the PLGA/PLLA polymer scaffold, 1% HA-PLGA/PLLA composite scaffold, and 5% HA-PLGA/PLLA composite scaffold. Cells in PLGA/PLLA maintained a round chondrocytic morphology (A) with the collagen matrix in the pericellular region (B). Note the meshwork of the cell-associated matrix. (C) Cells seeded on 1% HA-PLGA/PLLA composite scaffolds exhibit elongated morphology. Note the assembly of the matrix consisting of fibrous elements around the cell. Cells seeded on the 5% HA-PLGA/PLLA composite scaffolds showed organized collagen fibers (E, arrow) on the periphery of the cells (D–F).