Table 1.
C57 | C57Bx129 | ||
---|---|---|---|
Resistance (cmH2O s•ml−1) | p-value | ||
Respiratory System | 2.0 ± 0.2 | 1.6 ± 0.1 | 0.207 |
Isolated Lung | 1.5 ± 0.2 | 1.2 ± 0.2 | 0.403 |
Chest Wall | 0.4 ± 0.2 | 0.3 ± 0.2 | 0.671 |
Compliance (ml/cmH2O) | p-value | ||
Respiratory System | 0.021 ± 0.001 | 0.019 ± 0.002 | 0.180 |
Isolated Lung | 0.024 ± 0.001 | 0.023 ± 0.002 | 0.164 |
Mechanics of the respiratory system and its individual components analyzed in both C57BL/6J (C57; n=8) and C57BL/6×129 (C57×129; n=9) mice were assessed using a 1.2-second, 2.5 Hz forced oscillation maneuver and a 3-second low frequency forced oscillation of mutually prime frequencies between 1–20.5 Hz. Data analyzed by one-way ANOVA, presented as mean ± SE.