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Replication kinetics of the wild-type and mutant viruses. Confluent Vero cell monolayers were infected with each virus in triplicate at either a low MOI (0.2) (A) or a high MOI (3.0) (B), and viral titers were obtained by plaque assay on Vero cells at 24 and 48 hpi. Error bars represent standard deviations.
