Fig 2.

GP of EBOV, not whole EBOV particles, induces the formation of homotypic clusters. (A) Schematic representation of the viral particles used in the study. The EBOV proteins and RNA are depicted in red and pink, respectively, and those of HPIV3 in blue and light blue, respectively; the inserted EGFP gene is depicted in green. (B) Western blot analysis of GP expressed by wt EBOV (lanes 2) or by HPIV3/ΔF-HN/EboGP (lanes 3) on days 1 and 2 postinfection. Lanes 1, protein standards; lanes 4, mock infection. (C) Formation of homotypic clusters of DC infected with HPIV3/ΔF-HN/GP, but not EBOV or HPIV3, on day 2 postinfection.