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Immunization schedule. Altogether seven naive woodchucks were immunized with a DNA prime and adenoviral boost regimen, three of them with a prolonged protocol (bottom). Two weeks after the last immunization, the woodchucks were challenged with WHV and HDV intravenously. ct, cardiotoxin; cop., copies; i.m., intramuscularly; gg, gene gun; i.v., intravenously.
