Fig 3.

Immune response in mice. Representative dot plots and summaric HDV-specific IFN-γ⁺ CD8⁺ (A) and IFN-γ⁺ CD4⁺ (B) responses are presented. The upper panels show the summaric results after stimulation of spleen cells with 4 pools containing up to 8 peptides each. The lower panels present the percentages of CD8⁺ or CD4⁺ and IFN-γ⁺ cells after restimulation with the single peptides of pool 1 (**, P < 0.005; ***, P < 0.0005). A representative dot plot for one mouse is presented in the middle panels.