Table 1.
Kinetics of HDV RNA and WHV DNA after WHV/HDV coinfectiona
| Woodchuck (inoculum) and RNA or DNA | Result at week: |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | |
| 37669 (109 copies of HDV and 105 copies of WHV) | |||||||||||
| HDV RNA | − | − | − | + | − | − | − | − | − | − | − |
| WHV DNA (PCR) | − | − | − | + | ++ | + | + | + | − | − | − |
| WHV DNA (spot blot) | − | − | − | − | − | − | − | − | − | − | − |
| 46950 (109 copies of HDV and WHV) | |||||||||||
| HDV RNA | − | + | + | + | + | + | NT | NT | NT | NT | NT |
| WHV DNA (PCR) | − | + | + | ++ | + | + | NT | NT | NT | NT | NT |
| WHV DNA (spot blot) | − | − | − | + | + | − | NT | NT | NT | NT | NT |
a
HDV RNA and WHV DNA were tested by PCR; WHV DNA was also tested by spot blot hybridization. −, not detectable; +, positive; ++, strong positive; NT, not tested.