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Effect of cholesterol on alphavirus fusion
| Virus | Viral titera |
Ratiob | |
|---|---|---|---|
| +cholesterol | −cholesterol | ||
| SFV | 9 × 107 | 8 × 102 | 1 × 105 |
| CHIKV | 9.7 × 107 | 2 × 102 | 5 × 105 |
| SINV | 4 × 106 | 9 × 102 | 4 × 103 |
Viral titers from fusion infection assays performed at pH 5.5 (SFV and CHIKV) or pH 5.0 (SINV).
Ratio of titers on cells ± cholesterol.
