Fig 2.

Location of RV148 subtype B strains in the global subtype B phylogeny. (a) Black circles depict RV148 B strains from the Western B radiation, and hollow circles depict RV148 strains from the B′ radiation. (b) Distribution of pairwise genetic distance within the cosmopolitan Western B epidemic (blue circles), among RV148 sequences from the Western B radiation (green circles), and between these two groups (red circles). This analysis was based on near-full-genome sequences from 344 cosmopolitan Western B strains that were sampled between 2000 and 2007. (c) Detail of a trio of RV148 strains with low genetic diversity (red boxes). (d) Subtree of the B′ radiation, where the RV148 strains are highlighted (red boxes). The phylogenetic trees were built using near-full-genome sequences. Numbers on the branches of the phylogenetic trees represent the percentage of bootstrap replicates supporting the relevant clusters.