Figure 5. SYK expression following chemical SYK inhibition and FOXO1 depletion.
(A) SYK transcript abundance in DLBCL cell lines was assessed by qRT-PCR following 24 hr of treatment with R406 or vehicle. (B) SYK transcript abundance in DLBCL cell lines treated with R406 or vehicle for 24 hr following transduction with indicated shRNA was analyzed by qRT-PCR. p-values for vehicle vs. R406 were determined with a one-sided Welch t-test. ***, p≤0.0001; **, p≤0.001; *, p≤0.01, #, p≤0.05. Error bars represent the SD of 3 independent assays in a representative experiment. See also Figure S5.
