Figure 7. SYK and PTEN copy number alterations in primary DLBCLs.
(A) SYK and PTEN copy numbers were assessed and associated with SYK and PTEN transcript levels in primary DLBCLs (n = 169). SYK and PTEN copy numbers and transcript abundance were derived from (Monti et al., 2012). p-values were determined with a one-sided t-test. Box plot (median, line; 25% and 75% quartile, box; whiskers, maximum to minimum). (B) Relative frequency of SYKAMP and PTENDEL was assessed in transcriptionally defined “BCR” type vs. other primary DLBCLs (n = 147 [tumors with high confidence classification into CCC categories]) (Monti et al., 2012). p-values were determined with two-sided Fisher exact test. See also Figure S7 and Table S2.
