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64Cu handling in rats with cirrhosis vs. LEC−/− rats. (A) Liver histology in healthy rats and cirrhotic rats after phenobarbitone plus repeated CCl4 for 3 mo (×100). (B) 64Cu activity in organs 3 h after injection of 64Cu–histidine. (C) 64Cu excretion in bile of cirrhotic rats versus LEC−/− rats. α-SMA = α-smooth muscle actin; H&E = hematoxylin and eosin.
