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DCs from MRL/lpr mice show a decrease in synthesis and ability to sustain IL-6 mRNA levels. Real-time PCR was performed on RNA isolated from LPS-stimulated BMDCs untreated (A) or treated (B) with DRB at the indicated time points. The data from three individual B6 (●) and six MRL/lpr (○) mice are plotted as %18S.
