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. Author manuscript; available in PMC: 2013 Jul 3.
Published in final edited form as: J Immunol. 2007 Apr 15;178(8):4803–4810. doi: 10.4049/jimmunol.178.8.4803

FIGURE 7.

FIGURE 7

TLR4-stimulated DCs from MRL/lpr mice are unable to sustain IκBα phosphorylation. BMDCs (2 × 106) from B6 and MRL/lpr mice were stimulated with LPS (15 μg/ml) (A) or poly(I:C) (50 μg/ml) (B) for the indicated time points. Phospho-IκBα, IκBα, and β-tubulin (A) or β-actin (B) expression in whole cell lysates was determined by immunoblotting. Data represent seven (A) and three (B) experiments.