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. Author manuscript; available in PMC: 2013 Jul 3.
Published in final edited form as: Hepatology. 2010 Aug;52(2):678–690. doi: 10.1002/hep.23721

Fig. 1.

Fig. 1

Tg expression of Cyp7a1 in the mouse liver prevented weight gain and reduced adiposity. Female WT or Cyp7a1-tg mice were fed either a chow diet or HFD for 4 months, and (A,B) the body weight, (C) body composition, (D) visceral fat mass, (E) H&E staining of adipocytes, and (F) food intake were determined. Results are expressed as means and standard errors (n =6–10). *Statistically significant difference (P < 0.05) versus WT mice on chow; **statistically significant difference (P < 0.05) versus WT mice on an HFD. Abbreviations: Tg, transgenic; WT, wild-type.