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. Author manuscript; available in PMC: 2013 Jul 3.
Published in final edited form as: Sci Am. 2009 Feb;300(2):44–51. doi: 10.1038/scientificamerican0209-44

Customized Structure.

Customized Structure

The particle is built with biocompatible materials: a cyclodextrin-containing polymer (CDP) with polyethylene glycol (PEG) stalks to which transferrin proteins (Tf) are attached. Inside, as many as 2,000 siRNA molecules—the therapeutic agents—are stored.