Table 3.
Human viruses targeted by novel miRNAsa
| Novel miRNA | Virus alignment position | Similarity with viral sequence (%) | Viral reference | Viral pathogen targeted |
|---|---|---|---|---|
| SX1 | 66169-66188 | 94.12 | NC_001806.1 | HSVb1 |
| SX1 | 68339-68357 | 100.00 | NC_001806.1 | HSV 1 |
| SX1 | 66642-66661 | 94.12 | NC_001798.1 | HSV 2 |
| SX1 | 47189-47209 | 88.24 | NC_001798.1 | HSV 2 |
| SX1 | 110945-110963 | 93.75 | NC_009333.1 | HHVc 8 |
| SX4 | 108825-108848 | 85.71 | NC_001806.1 | HSV 1 |
| SX5 | 10577-10602 | 82.61 | NC_001544.1 | Ross River virus |
| SX5 | 1359-1382 | 90.00 | NC_002058.3 | Poliovirus |
| SX5 | 12789-12815 | 83.33 | NC_001454.1 | Human adenovirus F |
| SX5 | 111492-111516 | 86.36 | NC_009334.1 | HHV 4 |
| SX5 | 110662-110686 | 86.36 | NC_009334.1 | HHV 4 type 1 |
| SX5 | 3519-3543 | 85.71 | NC_001355.1 | HPVd type 6b |
| SX5 | 5144-5165 | 90.00 | NC_011800.1 | HTLVe 4 |
| SX6 | 5751-5774 | 81.82 | NC_012801.1 | Human cosavirus B1 |
| SX6 | 2590-2615 | 85.00 | NC_014336.1 | Human enterovirus 109 |
| SX6 | 63066-63091 | 85.71 | NC_001806.1 | HSV 1 |
| SX6 | 30823-30845 | 90.00 | NC_001798.1 | HSV 2 |
| SX6 | 121985-122008 | 95.00 | NC_009334.1 | HHV 4 |
| SX6 | 121158-121181 | 95.00 | NC_007605.1 | HHV 4 type 1 |
| SX6 | 118479-118501 | 100.00 | NC_009333.1 | HHV 8 |
| SX6 | 4744-4765 | 85.00 | NC_005134.2 | HPV type 96 |
| SX6 | 4424-4444 | 85.00 | NC_003417.1 | Mayaro virus |
| SX6 | 154110-154139 | 70.83 | NC_001611.1 | Variola virus |
| SX7 | 26772-26791 | 80.95 | NC_011203.1 | Human adenovirus B1 |
| SX7 | 48845-48867 | 85.71 | NC_001806.1 | HSV 1 |
| SX7 | 49070-49091 | 85.71 | NC_001798.1 | HSV 2 |
| SX7 | 70373-70397 | 85.71 | NC_001798.1 | HSV 2 |
| SX7 | 147020-147044 | 90.91 | NC_009334.1 | HHV 4 |
| SX7 | 33604-33627 | 85.7 | NC_006273.2 | HHV 5 |
| SX7 | 57193-57216 | 85.00 | NC_009333.1 | HHV 8 |
| SX7 | 2455-2482 | 84.00 | NC_014952.1 | HPV type 128 |
a
Potential target viral for novel miRNAs were identified by scanning of viral reference sequences from NCBI (ftp://ftp.ncbi.nih.gov/refseq/release/viral/) using miRanda [16].
b
HSV= herpes simplex virus
c
HHV = human herpes virus
d
HPV = human papilloma virus
e
HTLV = human T-lymphotropic virus