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. Author manuscript; available in PMC: 2013 Jul 3.
Published in final edited form as: J Clin Immunol. 2011 May 11;31(4):666–680. doi: 10.1007/s10875-011-9541-7

Figure 2.

Figure 2

Th2 differentiated CD4 T cells are reduced in the lymph nodes of EC-OVA sensitized MIF-KO mice. (A) OVA-stimulation increases the number of IL-4 producing CD4 T-cells, measured by flow cytometry, to a greater degree in the WT, compared to MIF-KO system. (B&C) Both Th1 and Th2 differentiation, measured by upregulation of transcription factors Tbet and Gata3, are decreased in MIF-KO lymph nodes. Unsensitized (n=3), WT (n=3), MIF-KO (n=3). Summary data are pooled from three independent expeirments *** p<0.001, **p<0.01, *p<0.05.