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. Author manuscript; available in PMC: 2013 Jul 3.
Published in final edited form as: J Clin Immunol. 2011 May 11;31(4):666–680. doi: 10.1007/s10875-011-9541-7

Figure 8.

Figure 8

MIF receptor (CD74) deficiency attenuates Th2 but not Th1 cytokine production in skin-draining LN cells after EC OVA exposure to a greater extent than does MIF deficiency. Mice were EC exposed to OVA on day 0 and axillary LNs were harvested on day 4. LN cells were restimulated in vitro with OVA and, after 48 hours, cytokine levels in culture supernatants were measured. WT: n=5, MIF-KO: n=5, CD74-KO n=5. Each panel is representative of three separate experiments. *** p<0.001, **p<0.01, *p<0.05.