Table 4.
QTc formula | Mean QTc (ms) | Long Mean QTc [Male / Female] | QTc > 500 ms Burden (%) |
---|---|---|---|
Mean ± SD (range) | n, % | Mean ± SD (range) | |
Bazett | 447.31 ± 30.26 (381.56 to 550.98) | 19 (13.1%) [7 (4.8%) / 12 (8.3%)] | 8.22 ± 20.66 (0.00 to 99.80) |
Fridericia | 438.23 ± 29.37 (386.79 to 548.08) | 14 (9.7%) [6 (4.1%) / 8 (5.5%)] | 4.77 ± 16.92 (0.00 to 99.80) |
Framingham | 436.50 ± 28.37 (384.42 to 547.00) | 13 (9%) [5 (3.4%) / 8 (5.5%)] | 4.08 ± 16.11 (0.00 to 99.80) |
Study specific (log) | 433.69 ± 30.90 (369.25 to 546.60) | 14 (9.7%) [6 (4.1%) / 8 (5.5%)] | 4.28 ± 16.21 (0.00 to 99.60) |
Study specific (linear) | 433.45 ± 29.72 (374.19 to 546.10) | 13 (9%) [5 (3.4%) / 8 (5.5%)] | 3.83 ± 15.60 (0.00 to 99.40) |
Subject specific (log) | 435.66 ± 33.74 (373.10 to 553.26) | 17 (11.7%) [8 (5.5%) / 9 (6.2%)] | 5.16 ± 19.12 (0.00 to 99.80) |
Subject specific (linear) | 436.61 ± 33.33 (372.02 to 555.83) | 17 (11.7%) [8 (5.5%) / 9 (6.2%)] | 5.09 ± 19.11 (0.00 to 99.7) |
linear, linear QT/RR regression line pattern; log, logarithmic QT/RR regression line pattern; ms, millisecond; QTc, QT interval corrected for heart rate; SD, standard deviation.