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. Author manuscript; available in PMC: 2014 Jul 15.
Published in final edited form as: Cancer. 2013 Apr 12;119(14):2582–2592. doi: 10.1002/cncr.28017

Figure 4.

Figure 4

USC cell lines are significantly more sensitive to epothilones when compared to paclitaxel. Representative dose-response curves and IC50 values as determined by flow cytometry after exposure to patupilone, ixabepilone and paclitaxel for 72 hours in USC-1 cell line are shown. IC50 values (mean) for patupilone, ixabepilone and paclitaxel are 0.41, 0.87 and 2.14 nM, respectively (paclitaxel vs patupilone: p = 0.003, paclitaxel vs ixabepilone: p = 0.02; patupilone vs ixabepilone: p = 0.02).