[a] Median OS of patients with stage III/IV pure USC, mixed USC, and OSC histologies was 221, 675, and 1306 days, respectively (p<0.0001). [b] Among patients with USC, tubulin-β-III overexpression stratifies poor clinical outcome. Median OS in patients with low and high expression was 615 versus 165 days, respectively (p=0.044). [c] In this same cohort, p-glycoprotein overexpression had no prognostic utility (p=0.69). Box-plots demonstrate median, interquartile range, and overall range of copy number values for [d] tubulin-β-III and [e] p-glycoprotein.