Table 3.
Cox proportional hazards models for 24-hour urine phosphorus excretion with all-cause mortality
Variable | UPE Tertiles | Continuous | |||
---|---|---|---|---|---|
Tertile 1 (<508 mg/d) | Tertile 2 (508–748 mg/d) | Tertile 3 (>748 mg/d) | Per 300 mg/d Higher UPE (95% CI) | P Value | |
Events/at risk (n/n) | 138/294 | 112/293 | 90/293 | 340/880 | |
Unadjusted: Hazard ratio (95% CI) | 1.00 (reference) | 0.74 (0.58 to 0.95) | 0.56 (0.43 to 0.74) | 0.81 (0.72 to 0.91) | <0.001 |
Model 1: Hazard ratio (95% CI) | 1.00 (reference) | 0.84 (0.65 to 1.08) | 0.72 (0.54 to 0.95) | 0.91 (0.80 to 1.03) | 0.14 |
Model 2: Hazard ratio (95% CI) | 1.00 (reference) | 0.92 (0.71 to 1.20) | 0.78 (0.56 to 1.07) | 0.96 (0.84 to 1.11) | 0.59 |
Model 1; adjusted for age, sex, oral estrogen use (women), race, and estimated GFR. Model 2; adjusted for age, sex, oral estrogen use (women), race, estimated GFR, diabetes, hypertension, smoking, body mass index, cholesterol, HDL cholesterol, C-reactive protein, and urine calcium excretion. UPE, urinary phosphorus excretion; CI, confidence interval.