Table 4.
Cox proportional hazards models for 24-hour urine phosphorus excretion with cardiovascular disease events
| Variable | UPE Tertiles | Continuous | |||
|---|---|---|---|---|---|
| Tertile 1 (<508 mg/d) | Tertile 2 (508–748 mg/d) | Tertile 3 (>748 mg/d) | Per 300 mg/d Higher UPE (95% CI) | P Value | |
| Events/at risk (n/n) | 91/294 | 68/293 | 62/293 | 221/880 | |
| Unadjusted: Hazard ratio (95% CI) | 1.00 (reference) | 0.67 (0.49 to 0.92) | 0.57 (0.42 to 0.79) | 0.76 (0.66 to 0.88) | <0.001 |
| Model 1: Hazard ratio (95% CI) | 1.00 (reference) | 0.77 (0.56 to 1.06) | 0.73 (0.52 to 1.03) | 0.84 (0.71 to 0.98) | 0.02 |
| Model 2; Hazard ratio (95% CI) | 1.00 (reference) | 0.79 (0.57 to 1.09) | 0.70 (0.47 to 1.03) | 0.81 (0.68 to 0.97) | 0.02 |
Model 1; adjusted for age, sex, oral estrogen use (women), race, and estimated GFR. Model 2; adjusted for age, sex, oral estrogen use (women), race, estimated GFR, diabetes, hypertension, smoking, body mass index, cholesterol, HDL cholesterol, C-reactive protein, and urine calcium excretion. UPE, urinary phosphorus excretion; CI, confidence interval.