Skip to main content
. 2013 Aug 1;36(8):1129–1138. doi: 10.5665/sleep.2870

Figure 3.

Figure 3

Diurnal variations in sleep/wake states. A and B, The diurnal pattern of wake and NREM sleep was almost identical in WT and Atx mice irrespective of the treatment (AAV-mCherry or AAV-orexin). C, However, Atx mice treated with AAV-mCherry had much less circadian variation in REM sleep than their WT littermates due to an increase in their REM sleep amount during the dark period. D, Injections of AAV-orexin caused a small and statistically insignifi cant decrease in cataplexy after dark onset in Atx mice. There were no changes in the amounts of sleep-wake states in WT mice treated with AAV-orexin. Data are shown in 2 h intervals. *P < 0.01 compared to WT AAV-mCherry mice. AAV, adeno-associated viral vector; Atx, transgenic (ataxin); NREM, nonrapid eye movement; REM, rapid eye movement; WT, wild type.