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. Author manuscript; available in PMC: 2013 Aug 3.
Published in final edited form as: Cell. 2012 Aug 3;150(3):521–532. doi: 10.1016/j.cell.2012.05.048

Figure 4. Bmb protein dynamics during mitosis.

Figure 4

(A) Bmb protein localizes as distinct foci to the mitotic spindle region during metaphase (n=4). (B) During anaphase Bmb is interspersed between the separating chromosomes (inset; n=3) and in the region of the mitotic spindle. (C) Later in anaphase, Bmb foci are decorating the chromosomes (inset; n=3). (D) At the 2 min time point Bmb surrounds the individual chromosomes, which are still separating (n=5). (E) Schematic summarizing Bmb localization during metaphase to anaphase/telophase. Arrows in the right panel indicate that the karyomeres will continue to move to their final central position in the cell. 0 min corresponds to metaphase at the 32-to-64 cell transition. Bmb (green), microtubules (DM1a, red), chromosomes (DAPI, white and blue in merge). Scale bar = 5 μm and insets show 2X enlargements. See also Figure S2.