Table 3.
Univariate analysis (binary logistic regression) for prescribing monotherapy versus combination therapy
| Variable | Reference category | β | p-value | Odds ratio with 95% CI |
|---|---|---|---|---|
| Gender |
Male |
0.43 |
0.14 |
1.5 (0.88 – 2.7) |
| Age |
Continuous variable |
0.008 |
0.5 |
1.0 (1.0-1.03) |
| Education |
School education |
0.338 |
0.4 |
1.4 (0.7-2.8) |
| Marital status |
Single |
−0.2 |
0.4 |
0.8 (0.5-1.3) |
| Smoking |
Not smoking |
0.45 |
0.04 |
1.7 (1.02-2.9) |
| Occupation |
Not working |
0.055 |
0.9 |
1.1 (0.5-2.2) |
| Waist circumferences |
Normal WC |
−0.16 |
0.5 |
0.9 (0.52-1.4) |
| Duration of psychiatric illness |
< 10 years |
0.7 |
0.01 |
2 (1.2-3.4) |
| Number of hospitalization |
< 2 |
1.02 |
0.001 |
2.8 (1.5-5.1) |
| Family history of DM |
No family history |
−0.16 |
0.53 |
0.9 (0.42-1.4) |
| Depot |
No depot |
2.0 |
< 0.001 |
7.4 (4.2-12.9) |
| Anticholinergic |
No anticholinergics |
1.9 |
<0.001 |
6.7 (3.5-12.8) |
| SGA |
No SGA |
−0.4 |
0.2 |
0.7 (0.4-1.2) |
| CPZeq | Continuous variable | −5.5 | <0.001 | 1.01 (1.0 – 1.01) |
Abbreviations: CI confidence interval, β coefficient of predictor variables, DM diabetes mellitus, SGA Second Generation Antipsychotic, CPZeq Chlorpromazine Dose Equivalencies.