Table 4. Top 10 genera generating the highest area under curves in a receiver operating characteristics curve.
Mann-Whitney | Median (25%/75%) | ||||
Family. Genus | AUC | P | P adj. | Neurotypical | Autistic |
Veillonellaceae.unknown_genus | 0.829 | 0.000 | 0.039 | 0.04(0.01/0.21) | 0(0/0.01) |
Prevotellaceae.Prevotella | 0.809 | 0.001 | 0.039 | 0.06(0.01/0.67) | 0(0/<0.01) |
Lachnospiraceae.Coprococcus | 0.800 | 0.001 | 0.062 | 0.03(0.02/0.05) | 0.01(0/0.01) |
Lactobacillaceae.Lactobacillus | 0.771 | 0.003 | 0.096 | <0.01(0/<0.01) | 0.01(<0.01/0.04) |
Prevotellaceae.unknown_genus | 0.754 | 0.002 | 0.062 | <0.01(0/0.02) | 0(0/0) |
Alcaligenaceae.Sutterella | 0.746 | 0.004 | 0.096 | 0.06(0/0.18) | 0(0/0) |
Lachnospiraceae.Roseburia | 0.746 | 0.009 | 0.139 | 0.06(0.03/0.18) | 0.02(0.01/0.05) |
Porphyromonadaceae.Butyricimonas | 0.712 | 0.007 | 0.139 | 0.01(0/0.09) | 0(0/0) |
Eubacteriaceae.Eubacterium | 0.709 | 0.026 | 0.277 | 0.03(0.02/0.10) | 0.13(0.05/0.25) |
Prevotellaceae.Paraprevotella | 0.703 | 0.009 | 0.139 | <0.01(0/0.35) | 0(0/0) |
A highest area under curves (AUC) value of 0.5 indicates no predictive, while an AUC of 1 indicates perfect ability to predict.