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Effect of a chronic treatment of 6-mo ATX mice with IVA (A) and METO (B) and exposure to voluntary PT (C) on the cerebral compliance expressed as circumferential strain (%), the distensibility expressed as ID (%/mmHg), and flow-mediated endothelium-dependent dilation of pressurized cerebral arteries. Results are means ± SE of 6 to 10 mice. *P < 0.05 vs. 6-mo WT mice; φP < 0.05 vs. 6-mo ATX mice.
