Table I.
Authors, year (Ref.) | Age (years)/gender | Tumor location | SPE/IE | Bence-Jones protein | Previously diagnosed PCN | Type of EMP | Clinical manifestations | Treatment | Outcome |
---|---|---|---|---|---|---|---|---|---|
Knudsen O, 1937 (5) | 46/F | NA | NA | NA | None | P | Palpable mass | Radical nephrectomy | NA |
Farrow GM et al, 1968 (6) | 53/M | L | NA | NA | NA | P | NA | Radical nephrectomy, radiotherapy | Succumbed after 16 years |
Solomito VL et al, 1972 (7) | 64/M | L | NA | NA | Nasopharynx | S | Palpable mass, fatigue | Radical nephrectomy, ileocolectomy | Alive after 4.5 years |
Catalona WJ et al, 1974 (8) | 52/F | R | β ↑ | + | Temporal lobe | S | Palpable mass | Biopsy, radiotherapy, chemotherapy | NA |
Siemers PT et al, 1977 (9) | 56/M | L | Normal | NA | None | P | Anorexia, fatigue, palpable mass | Radical nephrectomy, radiotherapy, hemodialysis | Alive after 3 months |
Morris SA et al, 1977 (10) | 50/M | L | IgM ↑ | + | Skull, scapula | S | Gross hematuria | Radical nephrectomy, radiotherapy | NA |
Silver TM et al, 1977 (11) | 40/M | L | Normal | - | None | P | Gross hematuria, flank pain | Radical nephrectomy | NA |
Kandel LB et al, 1984 (12) | 55/M | R | γ ↑ | + | None | p | Burning feeling, | Radical nephrectomy, radiotherapy | NA |
Jaspan T et al, 1984 (13) | 75/F | L | IgG ↑ | + | None | P | Back pain | Biopsy | Succumbed after biopsy |
Kanoh T et al, 1987 (14) | 50/M | R | IgA ↑ | NA | MM | S | Microscopic hematuria, abdominal fullness | Chemotherapy, radiotherapy | Succumbed after 2 years |
Igel TC et al, 1991 (15) | 64/M | L | IgM ↑ | NA | None | P | Burning feeling, weight loss | Radical nephrectomy, radiotherapy, chemotherapy | NA |
Kanoh T et al, 1992 (16) | 76/F | NA | NA | NA | None | P | NA | Radical nephrectomy | Succumbed after 3 months |
Kanoh T et al, 1993 (17) | 43/M | R | NA | + | Spinal bones | S | Paraplegia | Radiotherapy | NA |
Rebelakos AG et al, 1995 (18) | 52/F | R | NA | NA | T9 vertebra | S | Gross hematuria, back pain, palpable mass | Radical nephrectomy | Alive after 6 months |
Shustik C et al, 1995 (19) | 31/M | NA | IgG ↑ | NA | None | P | Asymptomatic | Radical nephrectomy | Alive after 33 months |
Manseck A et al, 1997 (20) | 64/NA | NA | NA | - | None | P | NA | Radical nephrectomy | NA |
Tejido Sanchez A et al, 2001 (21) | 59/NA | R | NA | NA | None | P | NA | Chemotherapy | Succumbed after 1 year |
Kim SH et al, 2003 (22) | 44/F | R | NA | NA | MM | S | Palpable mass | Surgery, chemotherapy, radiotherapy | Alive after 3 months |
Fan F et al, 2005 (23) | 61/F | R | NA | NA | None | P | Back pain | Partial nephrectomy, chemotherapy | Alive after 2.5 year |
Park SY et al, 2007 (24) | 39/M | L | Normal | NA | None | P | NA | Radical nephrectomy | Succumbed after 34 months |
Yazici S et al, 2009 (25) | 67/F | L | α2 ↑, γ ↑ | NA | None | P | Asymptomatic | Radical nephrectomy | Alive after 6 months |
Mongha R et al, 2010 (26) | 58/M | R | Normal | - | None | P | Lumbar pain | Radical nephrectomy, radiotherapy | Alive after 1 year |
Yang GF et al, 2010 (27) | 76/F | L | NA | NA | None | P | Back pain | Radical nephrectomy | NA |
Zhong Y et al, 2010 (28) | 41/M | L | NA | - | None | P | Epigastric discomfort | Radical nephrectomy | NA |
Present case | 46/F | L | γ ↑, α1 ↑ | + | None | P | NA | Radical nephrectomy | Alive after 6 months |
F, female; M, male; L, left kidney; R, right kidney; NA, not available; SPE, serum protein electrophoresis; IE, immunoelectrophoresis;
↑, increased;
+, positive;
−, negative; PCN, plasma cell neoplasm; MM, multiple myeloma; EMP, extramedullary plasmacytoma; P, primary; S, secondary.