Figure 5.

Western blotting analysis of (A) caspase-3, Bax and Bcl-2, and (B) cyclin D1, ERK and pERK, in Eca109 cell lines. The four groups were control (C), flavopiridol only (F), radiation only (R) and flavopiridol with radiation (FR). (A) The level of caspase-3 and Bax in FR increased significantly and the level of Bcl-2 in FR decreased significantly. (B) The level of cyclin D1 in FR was decreased significantly, while there was no significant difference in all groups about the level of ERK/pERK.