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Effect of ECRG4 on cell cycle- and apoptosis-related proteins. (A) Cyclin A expression significantly decreased, while there was no significant difference in Cyclin E expression. (B) ECRG4 increased the Bax expression and decreased the Bcl-2 expression. (C) Overexpression of ECRG4 resulted in the inhibition of phosphorylation of AKT in the M2 cells. The results are of one representative experiment among three runs that showed similar patterns with one another.
