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. 2013 Jul 3;8(7):e67759. doi: 10.1371/journal.pone.0067759

Table 1. Characteristics in patients with prediabetes according to glucose tolerance.

Variables All (n = 1197) NGT (n = 837) IGT (n = 309) 2-h NDM (n = 51) P
Male gender, n (%) 606 (50.6) 447 (53.4) 136 (44.0) 23 (45.1) 0.01
Age, years 56.5±10.3 55.8±10.6 57.5±9.4 60.8±8.8 0.001
Smoking (%) 430 (35.9) 321 (38.4) 95 (30.7) 14 (27.5) 0.03
Drinking (%) 285 (23.7) 211 (25.2) 67 (21.7) 7 (13.7) 0.10
BMI, kg/m2 24.9±3.2 24.5±3.1 25.5±3.3 25.7±3.5 <0.001
SBP, mm Hg 141.4±20.1 139.8±19.7 145.1±21.1 146.6±20.7 <0.001
DBP, mm Hg 87.6±9.8 87.2±9.8 88.7±9.7 88.2±8.9 0.05
Hypertension (%) 320 (26.7) 189 (22.6) 105 (34.0) 26 (51.0) <0.001
Total cholesterol, mmol/l 5.14±0.99 5.09±1.00 5.24±0.96 5.31±1.01 0.04
HDL cholesterol, mmol/l 1.30±0.31 1.31±0.30 1.27±0.31 1.26±0.30 0.05
LDL cholesterol, mmol/l 3.06±0.71 3.03±0.72 3.14±0.69 3.15±0.72 0.05
Triglycerides, mmol/l 1.64±1.53 1.51±1.36 1.91±1.88 2.04±1.76 <0.001
Log-CRP, mmol/l 0.92±0.91 0.86±0.95 1.03±0.86 1.19±0.78 0.007
Creatinine, mmol/l 68.1±16.3 68.7±16.4 66.7±16.3 68.9±14.9 0.19
FPG, mg/dl 104.40±12.60 102.62±10.87 108.04±12.72 111.62±10.86 <0.001
2-h PG, mg/dl 7.0±1.3 5.9±1.2 9.0±0.9 12.3±1.2 <0.001
HbA1c, % 5.9±0.3 5.9±0.3 6.0±0.3 6.2±0.4 <0.001
SUA, mg/dl 5.1±1.5 5.0±1.5 5.3±1.6 5.6±1.8 0.001
Hyperuricemia (%) 170 (14.2) 103 (12.3) 53 (17.2) 14 (27.5) 0.002
e-GFR, ml/min per 1.73 m2 97.8±16.0 98.4±16.1 98.0±16.2 97.8±14.2 0.52

Data were presented as mean (± SD) or number (%). Means and proportions were compared by ANOVA and Fisher’s exact test, respectively. P values testing the overall difference among NGT, IGT and 2-h NDM groups. Definitions of hypertension, hyperuricemia, 2-h NDM (2-h newly diagnosed diabetes) were in methods. BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL, high density lipoprotein; LDL, low density lipoprotein; log-CRP, logarithmic transformed C-reactive protein; FPG, fasting plasma glucose; 2-h PG, 2 hour postload glucose; SUA, serum uric acid; e-GFR, estimated glomerular filtration rate. International system of units (SI) conversion: plasma glucose 1 mg/dl = 1/18 mmol/l; SUA 1 mg/dl = 59.5 µmol/l.