Table 1. Characteristics in patients with prediabetes according to glucose tolerance.
Variables | All (n = 1197) | NGT (n = 837) | IGT (n = 309) | 2-h NDM (n = 51) | P |
Male gender, n (%) | 606 (50.6) | 447 (53.4) | 136 (44.0) | 23 (45.1) | 0.01 |
Age, years | 56.5±10.3 | 55.8±10.6 | 57.5±9.4 | 60.8±8.8 | 0.001 |
Smoking (%) | 430 (35.9) | 321 (38.4) | 95 (30.7) | 14 (27.5) | 0.03 |
Drinking (%) | 285 (23.7) | 211 (25.2) | 67 (21.7) | 7 (13.7) | 0.10 |
BMI, kg/m2 | 24.9±3.2 | 24.5±3.1 | 25.5±3.3 | 25.7±3.5 | <0.001 |
SBP, mm Hg | 141.4±20.1 | 139.8±19.7 | 145.1±21.1 | 146.6±20.7 | <0.001 |
DBP, mm Hg | 87.6±9.8 | 87.2±9.8 | 88.7±9.7 | 88.2±8.9 | 0.05 |
Hypertension (%) | 320 (26.7) | 189 (22.6) | 105 (34.0) | 26 (51.0) | <0.001 |
Total cholesterol, mmol/l | 5.14±0.99 | 5.09±1.00 | 5.24±0.96 | 5.31±1.01 | 0.04 |
HDL cholesterol, mmol/l | 1.30±0.31 | 1.31±0.30 | 1.27±0.31 | 1.26±0.30 | 0.05 |
LDL cholesterol, mmol/l | 3.06±0.71 | 3.03±0.72 | 3.14±0.69 | 3.15±0.72 | 0.05 |
Triglycerides, mmol/l | 1.64±1.53 | 1.51±1.36 | 1.91±1.88 | 2.04±1.76 | <0.001 |
Log-CRP, mmol/l | 0.92±0.91 | 0.86±0.95 | 1.03±0.86 | 1.19±0.78 | 0.007 |
Creatinine, mmol/l | 68.1±16.3 | 68.7±16.4 | 66.7±16.3 | 68.9±14.9 | 0.19 |
FPG, mg/dl | 104.40±12.60 | 102.62±10.87 | 108.04±12.72 | 111.62±10.86 | <0.001 |
2-h PG, mg/dl | 7.0±1.3 | 5.9±1.2 | 9.0±0.9 | 12.3±1.2 | <0.001 |
HbA1c, % | 5.9±0.3 | 5.9±0.3 | 6.0±0.3 | 6.2±0.4 | <0.001 |
SUA, mg/dl | 5.1±1.5 | 5.0±1.5 | 5.3±1.6 | 5.6±1.8 | 0.001 |
Hyperuricemia (%) | 170 (14.2) | 103 (12.3) | 53 (17.2) | 14 (27.5) | 0.002 |
e-GFR, ml/min per 1.73 m2 | 97.8±16.0 | 98.4±16.1 | 98.0±16.2 | 97.8±14.2 | 0.52 |
Data were presented as mean (± SD) or number (%). Means and proportions were compared by ANOVA and Fisher’s exact test, respectively. P values testing the overall difference among NGT, IGT and 2-h NDM groups. Definitions of hypertension, hyperuricemia, 2-h NDM (2-h newly diagnosed diabetes) were in methods. BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL, high density lipoprotein; LDL, low density lipoprotein; log-CRP, logarithmic transformed C-reactive protein; FPG, fasting plasma glucose; 2-h PG, 2 hour postload glucose; SUA, serum uric acid; e-GFR, estimated glomerular filtration rate. International system of units (SI) conversion: plasma glucose 1 mg/dl = 1/18 mmol/l; SUA 1 mg/dl = 59.5 µmol/l.