Figure 2. Candidate susceptibility region 12q24.12 identified by the combination of results obtained with array-CGH and published genome-wide association studies (GWAS) in related diseases.
a) description of the region, b) location of the MCR identified in our array-CGH analysis, c) previously described CNVs in the region, d) SNPs selected for our genotyping analysis, e) linkage disequilibrium (LD) structure across the 12q24.12 locus. The LD structure has been obtained with Haploview software v.4.3, based on r2 coefficient calculated with the CEU HapMap database.