Figure 2. Serum concentrations of proinflammatory cytokines are increased in the frail elderly (FE; n=30, average age=80) relative to adult donors (AD; n=10, average age=31).

For IFN-γ, 60% of adult donors did not meet the limit of detection; for IL-1β, all of the adults and 60% of frail elderly donors did not meet the limit of detection. Differences determined by the Kruskal-Wallis test with adjustments to control for FDR. ***P < 0.001; **P < 0.01; *P < 0.05.