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. 2013 Apr;93(4):633–637. doi: 10.1189/jlb.0912461

Table 1. Comparison of Age-Stratified Senior and Frail Elderly Donors and Associations with Previous Cancer Status.

Characteristic Seniors Frail elderly Pval Previous cancer status
Pval
Negative Positive
Sample size 24 26 148 23
Age range (median) 68–76 (71) 67–80 (74) 61–99 (84) 68–99 (86)
CD45+ leukocytes 6811 ± 961 5440 ± 298 NS 5844 ± 257 6077 ± 471 NS
Monocytes 5.29 ± 0.41 4.55 ± 0.30 NS 5.42 ± 0.37 5.45 ± 0.16 NS
MDSCs
    CD33+HLA-DR 0.29 ± 0.04 0.33 ± 0.05 NS 0.35 ± 0.02 0.56 ± 0.10 0.031
    CD11b+CD15+ subset 0.16 ± 0.04 0.24 ± 0.05 0.046 0.23 ± 0.02 0.44 ± 0.09 0.030

Means and se are presented. CD45+ leukocytes are presented as per microliter of whole blood, whereas values for all other subsets are relative to values established for CD45+ leukocytes. Comparisons were performed by linear regression on log-transformed values, adjusting for age, sex, and cohort (where applicable, see Materials and Methods). Comparison-wise P values (Pval) are presented.

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