Table IV.
Odds of Caregiver-Reported Nonadherence on Social Ecological Predictors (Based on GEE Model With Repeated Measures Unadjusted for Other Predictors)
| Predictors | Odds ratio | 95% LCI | 95% UCI | p-value |
|---|---|---|---|---|
| Regimen and regimen complexity at baseline | ||||
| On PI | 0.91 | 0.44 | 1.88 | .802 |
| Maximum daily dose (of drug with largest dose) | 0.51 | 0.16 | 1.68 | .273 |
| Total number of doses per day (whole regimen) | 0.87 | 0.70 | 1.07 | .195 |
| Individual child factors | ||||
| Youth knows HIV status | 3.27 | 1.70 | 6.28 | <.001 |
| Full-scale IQ | 1.00 | 0.99 | 1.02 | .806 |
| BASC-PRS internalizing problems | 1.00 | 0.97 | 1.03 | .979 |
| BASC-PRS externalizing problems | 1.01 | 0.99 | 1.04 | .262 |
| BASC-SRP emotional symptoms | 1.01 | 0.98 | 1.05 | .494 |
| BASC-SRP school maladjustment | 1.00 | 0.97 | 1.03 | .802 |
| Family factors | ||||
| Caregiver well-being | 0.75 | 0.62 | 0.92 | .007 |
| Caregiver belief about HIV | 0.92 | 0.60 | 1.40 | .683 |
| Degree of caregiver responsibility | ||||
| Caregiver fully responsible for medication | 0.62 | 0.36 | 1.07 | .089 |
| BASC-SRP relation to parents | 0.98 | 0.95 | 1.00 | .054 |
| Caregiver: biological parent/relative | 0.88 | 0.49 | 1.59 | .684 |
| Extrafamilial factors | ||||
| Caregiver satisfaction w/social support | 1.06 | 0.75 | 1.49 | .756 |
| Youth satisfaction w/social support | 1.25 | 0.84 | 1.86 | .267 |
| At least one call to clinic | 1.13 | 0.47 | 2.71 | .790 |
| Number of recent stressful life events | 1.11 | 0.92 | 1.35 | .270 |