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. 2013 Apr 10;6(4):977–992. doi: 10.1242/dmm.010975

Fig. 1.

Fig. 1.

Hierarchical clustering analysis of differential DNA methylation enrichment peaks from arrays examining the effect of continuous preference drinking on B6 male brains. To compare differentially enriched regions between ethanol-exposed and control mice, the normalized log2-ratio scan values were averaged and then used to calculate the M′ value [M′=Average(log2 MeDIPE/InputE) – Average(log2 MeDIPC/InputC)] for each probe. NimbleScan sliding-window peak-finding algorithm was run on this data to find the differential enrichment peaks (DEPs).