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. 2013 Mar 15;6(4):1021–1030. doi: 10.1242/dmm.011908

Fig. 4.

Fig. 4.

Effect of erythropoietin (EPO) on the cardiac dysfunction in wild-type mice that underwent cecal ligation and puncture (CLP). Representative M-mode echocardiograms (A), and percentage ejection fraction (B), fractional shortening (C) and fractional area of change(D) in wild-type mice 24 hours subsequent to CLP surgery. At 1 hour after induction of CLP, mice were treated either with EPO (1000 IU/kg s.c.) or vehicle (10 ml/kg 0.9% saline s.c.). (B–D) Sham + vehicle (n=3); sham + EPO (n=3); CLP + vehicle (n=9); CLP + EPO (n=10). Data are expressed as means ± s.e.m. for n number of observations. P<0.05 versus CLP + vehicle.